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International consensus on allergy immunotherapy.

Identifieur interne : 002C23 ( Main/Exploration ); précédent : 002C22; suivant : 002C24

International consensus on allergy immunotherapy.

Auteurs : Marek Jutel [Pologne] ; Ioana Agache [Roumanie] ; Sergio Bonini [Royaume-Uni] ; A Wesley Burks [États-Unis] ; Moises Calderon [Royaume-Uni] ; Walter Canonica [Italie] ; Linda Cox ; Pascal Demoly [France] ; Antony J. Frew [Royaume-Uni] ; Robin O'Hehir [Australie] ; Jörg Kleine-Tebbe [Allemagne] ; Antonella Muraro [Italie] ; Gideon Lack [Royaume-Uni] ; Désirée Larenas [Mexique] ; Michael Levin [Afrique du Sud] ; Harald Nelson ; Ruby Pawankar [Japon] ; Oliver Pfaar [Allemagne] ; Ronald Van Ree [Pays-Bas] ; Hugh Sampson [États-Unis] ; Alexandra F. Santos [Royaume-Uni] ; George Du Toit [Royaume-Uni] ; Thomas Werfel [Allemagne] ; Roy Gerth Van Wijk [Pays-Bas] ; Luo Zhang [République populaire de Chine] ; Cezmi A. Akdis [Suisse]

Source :

RBID : pubmed:26162571

Descripteurs français

English descriptors

Abstract

Allergen immunotherapy (AIT) has been used to treat allergic disease since the early 1900s. Despite numerous clinical trials and meta-analyses proving AIT efficacious, it remains underused and is estimated to be used in less than 10% of patients with allergic rhinitis or asthma worldwide. In addition, there are large differences between regions, which are not only due to socioeconomic status. There is practically no controversy about the use of AIT in the treatment of allergic rhinitis and allergic asthma, but for atopic dermatitis or food allergy, the indications for AIT are not well defined. The elaboration of a wider consensus is of utmost importance because AIT is the only treatment that can change the course of allergic disease by preventing the development of asthma and new allergen sensitizations and by inducing allergen-specific immune tolerance. Safer and more effective AIT strategies are being continuously developed both through elaboration of new allergen preparations and adjuvants and alternate routes of administration. A number of guidelines, consensus documents, or both are available on both the international and national levels. The international community of allergy specialists recognizes the need to develop a comprehensive consensus report to harmonize, disseminate, and implement the best AIT practice. Consequently, the International Collaboration in Asthma, Allergy and Immunology, formed by the European Academy of Allergy and Clinical Immunology; the American Academy of Allergy, Asthma & Immunology; the American College of Allergy, Asthma & Immunology; and the World Allergy Organization, has decided to issue an international consensus on AIT.

DOI: 10.1016/j.jaci.2015.04.047
PubMed: 26162571


Affiliations:


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Le document en format XML

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<name sortKey="Van Ree, Ronald" sort="Van Ree, Ronald" uniqKey="Van Ree R" first="Ronald" last="Van Ree">Ronald Van Ree</name>
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<nlm:affiliation>Academic Medical Center, Departments of Experimental Immunology and of Otorhinolaryngology, University of Amsterdam, Amsterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
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<name sortKey="Sampson, Hugh" sort="Sampson, Hugh" uniqKey="Sampson H" first="Hugh" last="Sampson">Hugh Sampson</name>
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<nlm:affiliation>Department of Pediatrics, Division of Allergy-Immunology, and the Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai, New York, NY.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
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<region type="state">État de New York</region>
</placeName>
<wicri:cityArea>Department of Pediatrics, Division of Allergy-Immunology, and the Jaffe Food Allergy Institute at the Icahn School of Medicine at Mount Sinai, New York</wicri:cityArea>
</affiliation>
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<name sortKey="Santos, Alexandra F" sort="Santos, Alexandra F" uniqKey="Santos A" first="Alexandra F" last="Santos">Alexandra F. Santos</name>
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<nlm:affiliation>Department of Pediatric Allergy, Division of Asthma, Allergy & Lung Biology, King's College London, and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
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<placeName>
<settlement type="city">Londres</settlement>
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<name sortKey="Du Toit, George" sort="Du Toit, George" uniqKey="Du Toit G" first="George" last="Du Toit">George Du Toit</name>
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<nlm:affiliation>Department of Pediatric Allergy, Division of Asthma, Allergy & Lung Biology, King's College London, and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom.</nlm:affiliation>
<country xml:lang="fr">Royaume-Uni</country>
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<placeName>
<settlement type="city">Londres</settlement>
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<name sortKey="Werfel, Thomas" sort="Werfel, Thomas" uniqKey="Werfel T" first="Thomas" last="Werfel">Thomas Werfel</name>
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<nlm:affiliation>Department of Dermatology and Allergy, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover, Germany.</nlm:affiliation>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Dermatology and Allergy, Division of Immunodermatology and Allergy Research, Hannover Medical School, Hannover</wicri:regionArea>
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<region type="land" nuts="2">Basse-Saxe</region>
<settlement type="city">Hanovre</settlement>
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<name sortKey="Gerth Van Wijk, Roy" sort="Gerth Van Wijk, Roy" uniqKey="Gerth Van Wijk R" first="Roy" last="Gerth Van Wijk">Roy Gerth Van Wijk</name>
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<nlm:affiliation>Erasmus Medical Center, Rotterdam, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
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<settlement type="city">Rotterdam</settlement>
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<name sortKey="Zhang, Luo" sort="Zhang, Luo" uniqKey="Zhang L" first="Luo" last="Zhang">Luo Zhang</name>
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<nlm:affiliation>Beijing Institute of Otolaryngology, Beijing, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Beijing Institute of Otolaryngology, Beijing</wicri:regionArea>
<placeName>
<settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Akdis, Cezmi A" sort="Akdis, Cezmi A" uniqKey="Akdis C" first="Cezmi A" last="Akdis">Cezmi A. Akdis</name>
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<nlm:affiliation>Swiss Institute for Allergy and Asthma Research, University of Zurich, Christine Kühne-Center for Allergy Research and Education, Davos, Switzerland.</nlm:affiliation>
<country xml:lang="fr">Suisse</country>
<wicri:regionArea>Swiss Institute for Allergy and Asthma Research, University of Zurich, Christine Kühne-Center for Allergy Research and Education, Davos</wicri:regionArea>
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<settlement type="city">Zurich</settlement>
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<series>
<title level="j">The Journal of allergy and clinical immunology</title>
<idno type="eISSN">1097-6825</idno>
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<date when="2015" type="published">2015</date>
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<term>Adjuvants, Immunologic (administration & dosage)</term>
<term>Allergens (administration & dosage)</term>
<term>Allergens (immunology)</term>
<term>Consensus</term>
<term>Dermatitis, Atopic (immunology)</term>
<term>Dermatitis, Atopic (physiopathology)</term>
<term>Dermatitis, Atopic (therapy)</term>
<term>Desensitization, Immunologic (methods)</term>
<term>Desensitization, Immunologic (standards)</term>
<term>Food Hypersensitivity (immunology)</term>
<term>Food Hypersensitivity (physiopathology)</term>
<term>Food Hypersensitivity (therapy)</term>
<term>Humans</term>
<term>Immune Tolerance (drug effects)</term>
<term>International Cooperation</term>
<term>Practice Guidelines as Topic</term>
<term>Rhinitis, Allergic (immunology)</term>
<term>Rhinitis, Allergic (physiopathology)</term>
<term>Rhinitis, Allergic (therapy)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adjuvants immunologiques (administration et posologie)</term>
<term>Allergènes (administration et posologie)</term>
<term>Allergènes (immunologie)</term>
<term>Consensus</term>
<term>Coopération internationale</term>
<term>Désensibilisation immunologique ()</term>
<term>Désensibilisation immunologique (normes)</term>
<term>Eczéma atopique ()</term>
<term>Eczéma atopique (immunologie)</term>
<term>Eczéma atopique (physiopathologie)</term>
<term>Guides de bonnes pratiques cliniques comme sujet</term>
<term>Humains</term>
<term>Hypersensibilité alimentaire ()</term>
<term>Hypersensibilité alimentaire (immunologie)</term>
<term>Hypersensibilité alimentaire (physiopathologie)</term>
<term>Rhinite allergique ()</term>
<term>Rhinite allergique (immunologie)</term>
<term>Rhinite allergique (physiopathologie)</term>
<term>Tolérance immunitaire ()</term>
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<term>Adjuvants, Immunologic</term>
<term>Allergens</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en">
<term>Allergens</term>
</keywords>
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<term>Adjuvants immunologiques</term>
<term>Allergènes</term>
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<term>Immune Tolerance</term>
</keywords>
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<term>Allergènes</term>
<term>Eczéma atopique</term>
<term>Hypersensibilité alimentaire</term>
<term>Rhinite allergique</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en">
<term>Dermatitis, Atopic</term>
<term>Food Hypersensitivity</term>
<term>Rhinitis, Allergic</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Desensitization, Immunologic</term>
</keywords>
<keywords scheme="MESH" qualifier="normes" xml:lang="fr">
<term>Désensibilisation immunologique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr">
<term>Eczéma atopique</term>
<term>Hypersensibilité alimentaire</term>
<term>Rhinite allergique</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Dermatitis, Atopic</term>
<term>Food Hypersensitivity</term>
<term>Rhinitis, Allergic</term>
</keywords>
<keywords scheme="MESH" qualifier="standards" xml:lang="en">
<term>Desensitization, Immunologic</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Dermatitis, Atopic</term>
<term>Food Hypersensitivity</term>
<term>Rhinitis, Allergic</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Consensus</term>
<term>Humans</term>
<term>International Cooperation</term>
<term>Practice Guidelines as Topic</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Consensus</term>
<term>Coopération internationale</term>
<term>Désensibilisation immunologique</term>
<term>Eczéma atopique</term>
<term>Guides de bonnes pratiques cliniques comme sujet</term>
<term>Humains</term>
<term>Hypersensibilité alimentaire</term>
<term>Rhinite allergique</term>
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<front>
<div type="abstract" xml:lang="en">Allergen immunotherapy (AIT) has been used to treat allergic disease since the early 1900s. Despite numerous clinical trials and meta-analyses proving AIT efficacious, it remains underused and is estimated to be used in less than 10% of patients with allergic rhinitis or asthma worldwide. In addition, there are large differences between regions, which are not only due to socioeconomic status. There is practically no controversy about the use of AIT in the treatment of allergic rhinitis and allergic asthma, but for atopic dermatitis or food allergy, the indications for AIT are not well defined. The elaboration of a wider consensus is of utmost importance because AIT is the only treatment that can change the course of allergic disease by preventing the development of asthma and new allergen sensitizations and by inducing allergen-specific immune tolerance. Safer and more effective AIT strategies are being continuously developed both through elaboration of new allergen preparations and adjuvants and alternate routes of administration. A number of guidelines, consensus documents, or both are available on both the international and national levels. The international community of allergy specialists recognizes the need to develop a comprehensive consensus report to harmonize, disseminate, and implement the best AIT practice. Consequently, the International Collaboration in Asthma, Allergy and Immunology, formed by the European Academy of Allergy and Clinical Immunology; the American Academy of Allergy, Asthma & Immunology; the American College of Allergy, Asthma & Immunology; and the World Allergy Organization, has decided to issue an international consensus on AIT.</div>
</front>
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<name sortKey="Gerth Van Wijk, Roy" sort="Gerth Van Wijk, Roy" uniqKey="Gerth Van Wijk R" first="Roy" last="Gerth Van Wijk">Roy Gerth Van Wijk</name>
</country>
<country name="République populaire de Chine">
<noRegion>
<name sortKey="Zhang, Luo" sort="Zhang, Luo" uniqKey="Zhang L" first="Luo" last="Zhang">Luo Zhang</name>
</noRegion>
</country>
<country name="Suisse">
<region name="Canton de Zurich">
<name sortKey="Akdis, Cezmi A" sort="Akdis, Cezmi A" uniqKey="Akdis C" first="Cezmi A" last="Akdis">Cezmi A. Akdis</name>
</region>
</country>
</tree>
</affiliations>
</record>

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